Network-based screening identifies sitagliptin as an antitumor drug targeting dendritic cells.

Authors:
Ng II; Zhang J; Tian T; Peng Q; Huang Z and 5 more

Journal:
J Immunother Cancer

Publication Year: 2024

DOI:
10.1136/jitc-2023-008254

PMCID:
PMC10921530

PMID:
38458637

Journal Information

Full Title: J Immunother Cancer

Abbreviation: J Immunother Cancer

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Therapeutics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
5/6
83.3% Transparent
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Evidence found in paper:

"the computer code and data sets produced in this study are available in the following databases: the source code for compound screening is available at github ( https://github com/tiantz17/cmapfordc )."

Evidence found in paper:

"the computer code and data sets produced in this study are available in the following databases: the source code for compound screening is available at github ( https://github com/tiantz17/cmapfordc )."

Evidence found in paper:

"Competing interests: None declared."

Evidence found in paper:

"Funding: This study was supported by the National Key Research and Development Program of China (2020YFA0509400), National Natural Science Foundation of China (82073161, 32270982, 82241234), National Youth Talent Support Program, Tsinghua University Initiative Scientific Research Program, and Tsinghua-Peking University Center for Life Sciences (045-61020100119) to HT; National Natural Science Foundation of China (61872216, T2125007), the National Key Research and Development Program of China (2021YFF1201300), the Turing AI Institute of Nanjing, and the Tsinghua-Toyota Joint Research Fund to JZe; Health and Medical Research Fund of the Research Fund Secretariat, Food and Health Bureau, HKSAR, grant number 08193116."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025