A framework for inferring and analyzing pharmacotherapy treatment patterns.

"Declarations Ethics approval and consent to participateThis quality improvement study (ORAU000919) received a determination of Non-Research from Oak Ridge Sitewide Institutional Review Board (IRB00000547) (Oak Ridge, TN, USA). The study was approved based on an appropriate risk/benefit ratio and a study design wherein the risks have been minimized. Additionally, the Institutional Review Board (IRB) approved the investigator’s request for Waiver of Consent based on the applicable federal regulations, including DOE O443.1C. All privacy and security precautions as mandated by the IRB were followed. All methods were carried out in accordance with relevant guidelines and regulations. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This work was supported by U.S. Department of Veterans Affairs."