Neuroinflammation attenuation effects by celastrol and PDIA3 in the amygdala, hippocampus and dorsal raphe nucleus of obese mice.

"Declaration of competing interest The authors declare that there are no conflicts of interest."

"This work was supported by the grants from the Natural Science Foundation of Beijing Municipality (Grant No.: 7212185), the Scientific and Technological Innovation project of China Academy of Chinese Medical Sciences (Grant No.: CI2021A03808), the National Natural Science Foundation of China (Grant Nos.: 82330124, 81974526, and 82274176), the Innovation Team and Talents Cultivation Program of the National Administration of Traditional Chinese Medicine, China (Program No.: ZYYCXTD-C-202002), the Special Project for Training Outstanding Young Scientific and Technological Talents (innovative type) of Necessary Scientific Research Business Expenses of China Academy of Chinese Medical Sciences (Project Nos.: ZZ13-YQ-051, and ZZ15-YQ-063), and the Fundamental Research Funds for the Central public welfare research institutes (Grant No.: ZXKT21010). Chunyan Zhu: Design, Writing - Original draft preparation, and Funding acquisition; Xuemin Yao: Experiments, Writing - Original draft preparation; Dandan Liu: Methodology; Guoxin Zhang: Project administration; Yongping Zhu: Project administration; Hongyu Chi: Project administration; Shuangpan Zhang: Project administration; Jun Yang: Project administration; Ying Liu: Project administration; Jigang Wang: Writing - Reviewing and Editing; Na Lin: Design and Funding acquisition."