Routine evaluation of HBV-specific T cell reactivity in chronic hepatitis B using a broad-spectrum T-cell epitope peptide library and ELISpot assay.

"Declarations Ethics approval and consent to participateAll participants in this study provided written informed consent and Ethics committee approval conforming to the Declaration of Helsinki was obtained from Clinical Ethics Committee of Nanjing Second Hospital (ref: 2021-LS-ky013, 2021-LS-ky014). Consent for publicationNot applicable. Competing interestsThe authors declare no competing financial interests related to this study. Competing interests The authors declare no competing financial interests related to this study."

"Funding This work was supported by Jiangsu Provincial Science and Technology Fund of China (BE2017714), Nanjing Municipal Hygiene and Health Fund of Jiangsu Province (zkx18043), and Jiangsu Provincial Hygiene and Health Fund (M2020088), also supported in part by National Natural Science Foundation of China (82272402). The sponsors had no role in study design, data collection and analysis, preparation of the manuscript, or decision to submit the article for publication."