Combined IL6 and CCR2 blockade potentiates antitumor activity of NK cells in HPV-negative head and neck cancer.

"hpv + tumors) using the scrna-seq data from gse164690 (upper panel) and gse139324 (lower panel) we analyzed two public datasets available in the gene expression omnibus (geo) database gse164690 [ ] and gse139324 [ ].; availability of data and materials processed feature barcode matrices for all scrna-seq data are available on the geo database with accession number gse164690 and gse139324. availability of data and materials processed feature barcode matrices for all scrna-seq data are available on the geo database with accession number gse164690"

"Declarations Ethics approval and consent to participateAll animal experiments were approved by the Institutional Animal Care and Use Committee (IACUC) of Emory University and Augusta University. Consent for publicationAll authors read and approved the final manuscript. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was partially supported by NIH/NIDCR grants R01DE033691, R01DE033433, R01DE028351 and R03DE032084. The research was also supported by Imagine, Innovate and Impact (I3) Nexus Research Award from Emory School of Medicine through the Georgia CTSA NIH award (UL1-TR002378), Winship Invest$ Team Science Award, and Winship Invest$ Pilot Award under award number P30CA138292. Dr. Teng is the inaugural recipient of Winship Wally Award. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."