A randomized, double-blind, placebo-controlled, cross-over pilot study to investigate the efficacy of Rest-ZZZ formula in healthy participants with occasional sleeplessness.

"Declarations Conflict of interestJ.L. is the Chief Research Officer at LifeSeasons, Inc. M.M., E.L., M.E., D.C., and A.S. have no financial interests in or conflict with the subject matter or materials discussed. Ethics approvalThis study was approved by the Natural Health Product Directorate (NHPD), Health Canada, Ottawa, Ontario on August 26th, 2019. Research ethics board approval was granted on August 13th, 2019 by the Institutional Review Board IRB Services, Aurora, Ontario. The study was conducted in compliance with the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) Guideline for Good Clinical Practice (GCP) and in accordance with the Declaration of Helsinki guidelines and its subsequent amendments. This study was registered with ClinicalTrials.gov (NCT04093271). Consent to participateInformed consent was obtained from all individual participants included in this study. Conflict of interest J.L. is the Chief Research Officer at LifeSeasons, Inc. M.M., E.L., M.E., D.C., and A.S. have no financial interests in or conflict with the subject matter or materials discussed."

"Funding This study was funded by LifeSeasons, Inc."

"Declarations: Conflict of interestJ.L. is the Chief Research Officer at LifeSeasons, Inc. M.M., E.L., M.E., D.C., and A.S. have no financial interests in or conflict with the subject matter or materials discussed.: Ethics approvalThis study was approved by the Natural Health Product Directorate (NHPD), Health Canada, Ottawa, Ontario on August 26th, 2019. Research ethics board approval was granted on August 13th, 2019 by the Institutional Review Board IRB Services, Aurora, Ontario. The study was conducted in compliance with the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) Guideline for Good Clinical Practice (GCP) and in accordance with the Declaration of Helsinki guidelines and its subsequent amendments. This study was registered with ClinicalTrials.gov (NCT04093271).: Consent to participateInformed consent was obtained from all individual participants included in this study. Ethics approval: This study was approved by the Natural Health Product Directorate (NHPD), Health Canada, Ottawa, Ontario on August 26th, 2019. Research ethics board approval was granted on August 13th, 2019 by the Institutional Review Board IRB Services, Aurora, Ontario. The study was conducted in compliance with the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) Guideline for Good Clinical Practice (GCP) and in accordance with the Declaration of Helsinki guidelines and its subsequent amendments. This study was registered with ClinicalTrials.gov (NCT04093271)."