An integrative mechanistic model of thymocyte dynamics.

"Conflict of interest Author KP is an employee and shareholder of Modeling & Simulation Decisions FZ - LLC. Author GH is an employee of Biorchestra US, Inc. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The authors declare that this study received funding from Modeling & Simulation Decisions FZ - LLC. The funder was not involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision."

"The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Academic leadership program Priority 2030 proposed by the Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), the Ministry of Science and Higher Education of the Russian Federation (Agreement 075-10-2021-093, Project MMD-RND-2266) and Modeling & Simulation Decisions FZ - LLC, Dubai, UAE. GB was supported by the Moscow Center of Fundamental and Applied Mathematics (agreement with the Ministry of Education and Science of the Russian Federation No. 075-15-2022-286). VK and KP were supported by the Russian Science Foundation (Grant Number 23-71-10051)."