Modeling sporadic Alzheimer's disease in mice by combining Apolipoprotein E4 risk gene with environmental risk factors.

"Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."

"The author(s) declare financial support was received for the research, authorship, and/or publication of this article. BV is supported by the Helen and David Baffsky, Douglas and Alison Battersby/Veruse Pty Ltd., Boyarsky Family, Charlie Brockhoff, Andrew Michael and Michele Brooks, Tim Capelin, Pia Clinton-Tarestad, Dr Sophie and Mr Richard Gelski/Lawsam Foundation, John Gibb, Justin Greiner, Gordon Grieve, Gerry Harvey, Richard Holden/Station Capital, Tony and Vivienne Howland Rose, ISG Foundation, David and Lynn King, The Kirsch Foundation, Sam and Barbara Linz, Neill and Kathy Miller, Richard, Adrian, and Tom O’Connor, Katie Page, Marnie and Gary Perlstein, S & C Roth Family Foundation, John and Debbie Schaffer, David and Melanie Schwartz, Sealy of Australia and the Dyer Family, Julian Segal, John Singleton, Ashley Stephenson, Alex Sundich/Bridge Street Capital, and Tasmea Limited. The funders were not involved in the study design, analysis, interpretation of data, the writing of this article or the decision to submit it for publication."