Research Papers

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Exposure-response relationship of ramucirumab in RANGE, a randomized phase III trial in advanced urothelial carcinoma r…
de Wit R; Powles T; Castellano D; Necchi A; Lee JL; van der Heijden MS; Matsubara N; Bamias A; Fléchon A; Sternberg CN; Drakaki A; Yu EY; Zimmermann AH; Long A; Walgren RA; Gao L; Bell-McGuinn KM; Petrylak DP.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double-blind, placebo…
Ruijs TQ; Heuberger JAAC; de Goede AA; Ziagkos D; Otto ME; Doll RJ; van Putten MJAM; Groeneveld GJ.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Registered Funding Declared
Determinants of long-term opioid prescribing in an urban population: A cross-sectional study.
Naughton M; Redmond P; Durbaba S; Ashworth M; Molokhia M.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Risk of out-of-hospital cardiac arrest in antidepressant drug users.
Eroglu TE; Barcella CA; Gerds TA; Kessing LV; Zylyftari N; Mohr GH; Kragholm K; Polcwiartek C; Wissenberg M; Folke F; Tan HL; Torp-Pedersen C; Gislason GH.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Antiplatelet therapy in cardiovascular disease: Current status and future directions.
Passacquale G; Sharma P; Perera D; Ferro A.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Effects of dalteparin on anti-Xa activities cannot be predicted in critically ill COVID-19 patients.
van der Heijden CDCC; Ter Heine R; Kooistra EJ; Brüggemann RJ; Walburgh Schmidt JWJ; de Grouw EPLM; Frenzel T; Pickkers P; Leentjens J.
Br J Clin Pharmacol (Unknown)
Published: 2022
2/6 Transparent
Acute response to cholinergic challenge predicts long-term response to galantamine treatment in patients with Alzheimer…
Baakman AC; Gavan C; van Doeselaar L; de Kam M; Broekhuizen K; Bajenaru O; Camps L; Swart EL; Kalisvaart K; Schoonenboom N; Lemstra E; Scheltens P; Cohen A; van Gerven J; Groeneveld GJ.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Registered Funding Declared
A systematic review of methods used to conduct decentralised clinical trials.
Rogers A; De Paoli G; Subbarayan S; Copland R; Harwood K; Coyle J; Mitchell L; MacDonald TM; Mackenzie IS; Trials@Home Consortium.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Registered Funding Declared
Effective low-dose sirolimus regimen for kaposiform haemangioendothelioma with Kasabach-Merritt phenomenon in young inf…
Harbers VEM; van der Salm N; Pegge SAH; van der Vleuten CJM; Verhoeven BH; Vrancken SLAG; Schultze Kool LJ; Fuijkschot J; Te Loo DMMWM.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Health technology assessment of paediatric medicines: European landscape, challenges and opportunities inside the conec…
Moretti F; Ruiz F; Bonifazi F; Pizzo E; Kindblom JM; c4c HTA expert group.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Dissecting the IL-6 pathway in cardiometabolic disease: A Mendelian randomization study on both IL6 and IL6R.
Cupido AJ; Asselbergs FW; Natarajan P; CHARGE Inflammation Working Group; Ridker PM; Hovingh GK; Schmidt AF.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Code Funding Declared
Choice of oral anticoagulant prescribed by general practices in Wales: Application of Dirichlet regression and linked d…
Hill-McManus D; Hughes DA.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Emapalumab in primary haemophagocytic lymphohistiocytosis and the pathogenic role of interferon gamma: A pharmacometric…
Jacqmin P; Laveille C; Snoeck E; Jordan MB; Locatelli F; Ballabio M; de Min C.
Br J Clin Pharmacol (Unknown)
Published: 2021
3/6 Transparent
Funding Declared
A randomized study of the safety and pharmacokinetics of GSK3358699, a mononuclear myeloid-targeted bromodomain and ext…
Brown JA; Bal J; Simeoni M; Williams P; Mander PK; Soden PE; Daga S; Fahy WA; Wong GK; Bloomer JC; Erwig L; Cui Y; Fernando D; Carnaghan H; Banham-Hall EJ; Hopkins S; Davis BG; Oliveira JJD; Prinjha RK.
Br J Clin Pharmacol (Unknown)
Published: 2021
3/6 Transparent
Funding Declared
Integration of innovative statistical methods using genetic data provides pharmacological insight and facilitates drug …
Grant AJ.
Br J Clin Pharmacol (Unknown)
Published: 2021
1/6 Transparent
Safety and efficacy of fluvoxamine in COVID-19 ICU patients: An open label, prospective cohort trial with matched contr…
Calusic M; Marcec R; Luksa L; Jurkovic I; Kovac N; Mihaljevic S; Likic R.
Br J Clin Pharmacol (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
Efficacy and safety of tocilizumab versus standard care/placebo in patients with COVID-19; a systematic review and meta…
Vela D; Vela-Gaxha Z; Rexhepi M; Olloni R; Hyseni V; Nallbani R.
Br J Clin Pharmacol (Unknown)
Published: 2021
4/6 Transparent
Data Funding Declared
A case series of vaccine-induced thrombotic thrombocytopenia in a London teaching hospital.
Watts I; Smith D; Mounter S; Baker EH; Hitchings AW; Gill D.
Br J Clin Pharmacol (Unknown)
Published: 2021
3/6 Transparent
Funding Declared
Healthy volunteers in first-in-human oncology drug development for small molecules.
de Las Heras B; Bouyoucef-Cherchalli D; Reeve L; Reichl A; Mandarino D; Flach S; Vidal L; van Brummelen EMJ; Steeghs N.
Br J Clin Pharmacol (Unknown)
Published: 2021
1/6 Transparent
Combination therapies for COVID-19: An overview of the clinical trials landscape.
Akinbolade S; Coughlan D; Fairbairn R; McConkey G; Powell H; Ogunbayo D; Craig D.
Br J Clin Pharmacol (Unknown)
Published: 2021
3/6 Transparent
Funding Declared
Exposure-response analysis of acalabrutinib and its active metabolite, ACP-5862, in patients with B-cell malignancies.
Edlund H; Buil-Bruna N; Vishwanathan K; Wei H; Raman R; de Kock M; He Z; Liu H; Baek M; Ware J; Patel P; Tomkinson H; Sharma S.
Br J Clin Pharmacol (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
Evaluation of the drug-drug interaction potential of treosulfan using a physiologically-based pharmacokinetic modelling…
Schaller S; Martins FS; Balazki P; Böhm S; Baumgart J; Hilger RA; Beelen DW; Hemmelmann C; Ring A.
Br J Clin Pharmacol (Unknown)
Published: 2021
5/6 Transparent
Data Code Funding Declared
Preparation for the next pandemic-A plea for a nationalized approach.
Cohen A.
Br J Clin Pharmacol (Unknown)
Published: 2021
Better performance of medical students on pharmacotherapy knowledge and skills tests is associated with practising with…
Kalfsvel L; Versmissen J; van Doorn A; van den Broek W; van der Kuy H; van Rosse F.
Br J Clin Pharmacol (Unknown)
Published: 2021
3/6 Transparent
Funding Declared
Identifying adverse drug reactions from free-text electronic hospital health record notes.
Wasylewicz A; van de Burgt B; Weterings A; Jessurun N; Korsten E; Egberts T; Bouwman A; Kerskes M; Grouls R; van der Linden C.
Br J Clin Pharmacol (Unknown)
Published: 2021
1/6 Transparent