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Trem2 H157Y increases soluble TREM2 production and reduces amyloid pathology.
Qiao W; Chen Y; Zhong J; Madden BJ; Charlesworth CM; Martens YA; Liu CC; Knight J; Ikezu TC; Kurti A; Zhu Y; Meneses A; Rosenberg CL; Kuchenbecker LA; Vanmaele LK; Li F; Chen K; Shue F; Dacquel MV; Fryer J; Pandey A; Zhao N; Bu G.
Mol Neurodegener
(Unknown)
Published: 2023
FUS-ALS hiPSC-derived astrocytes impair human motor units through both gain-of-toxicity and loss-of-support mechanisms.
Stoklund Dittlau K; Terrie L; Baatsen P; Kerstens A; De Swert L; Janky R; Corthout N; Masrori P; Van Damme P; Hyttel P; Meyer M; Thorrez L; Freude K; Van Den Bosch L.
Mol Neurodegener
(Unknown)
Published: 2023
Alzheimer's disease: targeting the peripheral circulation.
Mol Neurodegener
(Unknown)
Published: 2023
Genome-wide association study of brain biochemical phenotypes reveals distinct genetic architecture of Alzheimer's dise…
Oatman SR; Reddy JS; Quicksall Z; Carrasquillo MM; Wang X; Liu CC; Yamazaki Y; Nguyen TT; Malphrus K; Heckman M; Biswas K; Nho K; Baker M; Martens YA; Zhao N; Kim JP; Risacher SL; Rademakers R; Saykin AJ; DeTure M; Murray ME; Kanekiyo T; Alzheimer’s Disease Neuroimaging Initiative; Dickson DW; Bu G; Allen M; Ertekin-Taner N.
Mol Neurodegener
(Unknown)
Published: 2023
Global neuropathologic severity of Alzheimer's disease and locus coeruleus vulnerability influences plasma phosphorylat…
Murray ME; Moloney CM; Kouri N; Syrjanen JA; Matchett BJ; Rothberg DM; Tranovich JF; Sirmans TNH; Wiste HJ; Boon BDC; Nguyen AT; Reichard RR; Dickson DW; Lowe VJ; Dage JL; Petersen RC; Jack CR; Knopman DS; Vemuri P; Graff-Radford J; Mielke MM.
Mol Neurodegener
(Unknown)
Published: 2022
Nuclear import receptors are recruited by FG-nucleoporins to rescue hallmarks of TDP-43 proteinopathy.
Khalil B; Chhangani D; Wren MC; Smith CL; Lee JH; Li X; Puttinger C; Tsai CW; Fortin G; Morderer D; Gao J; Liu F; Lim CK; Chen J; Chou CC; Croft CL; Gleixner AM; Donnelly CJ; Golde TE; Petrucelli L; Oskarsson B; Dickson DW; Zhang K; Shorter J; Yoshimura SH; Barmada SJ; Rincon-Limas DE; Rossoll W.
Mol Neurodegener
(Unknown)
Published: 2022
ApoE in Alzheimer's disease: pathophysiology and therapeutic strategies.
Mol Neurodegener
(Unknown)
Published: 2022
Liver-ing in your head rent free: peripheral ApoE4 drives CNS pathology.
Mol Neurodegener
(Unknown)
Published: 2022
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and br…
Fernández-Calle R; Konings SC; Frontiñán-Rubio J; García-Revilla J; Camprubí-Ferrer L; Svensson M; Martinson I; Boza-Serrano A; Venero JL; Nielsen HM; Gouras GK; Deierborg T.
Mol Neurodegener
(Unknown)
Published: 2022
17q21.31 sub-haplotypes underlying H1-associated risk for Parkinson's disease are associated with LRRC37A/2 expression …
Bowles KR; Pugh DA; Liu Y; Patel T; Renton AE; Bandres-Ciga S; Gan-Or Z; Heutink P; Siitonen A; Bertelsen S; Cherry JD; Karch CM; Frucht SJ; Kopell BH; Peter I; Park YJ; International Parkinson’s Disease Genomics Consortium (IPDGC); Charney A; Raj T; Crary JF; Goate AM.
Mol Neurodegener
(Unknown)
Published: 2022