Research Papers

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Phase 1 safety, tolerability, pharmacokinetics and pharmacodynamic results of KCL-286, a novel retinoic acid receptor-β…
Goncalves MB; Mant T; Täubel J; Clarke E; Hassanin H; Bendel D; Fok H; Posner J; Holmes J; Mander AP; Corcoran JPT.
Br J Clin Pharmacol (Unknown)
Published: 2023
4/6 Transparent
Registered Funding Declared
Cardiovascular concentration-effect relationships of amodiaquine and its metabolite desethylamodiaquine: Clinical and p…
Chan XHS; Chotsiri P; Capel RA; Pike J; Hanboonkunupakarn B; Lee SJ; Hanafiah M; Win YN; Cremer MA; Kiechel JR; Ogutu B; Taylor WRJ; Burton RB; Tarning J; White NJ.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Calcium-channel blockers: Clinical outcome associations with reported pharmacogenetics variants in 32 000 patients.
Türkmen D; Masoli JAH; Delgado J; Kuo CL; Bowden J; Melzer D; Pilling LC.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Data Funding Declared
Revisiting the inter-rater reliability of drug treatment assessments according to the STOPP/START criteria.
Parodi López N; Belfrage B; Koldestam A; Lönnbro J; Svensson SA; Wallerstedt SM.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Comparative assessment of viral dynamic models for SARS-CoV-2 for pharmacodynamic assessment in early treatment trials.
Agyeman AA; You T; Chan PLS; Lonsdale DO; Hadjichrysanthou C; Mahungu T; Wey EQ; Lowe DM; Lipman MCI; Breuer J; Kloprogge F; Standing JF.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Data Code
Local variation in low carbon footprint inhalers in pre-COVID pandemic primary care prescribing guidelines for adult as…
Twigg AJ; Wilkinson A; Smith JN.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
The Dutch chain approach on pharmaceuticals in water: Stakeholders acting together to reduce the environmental impact o…
Moermond CTA; de Rooy M.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
A crossover study evaluating the sex-dependent and sensitizing effects of sleep deprivation using a nociceptive test ba…
Hijma H; Koopmans I; Klaassen E; Doll RJ; Zuiker R; Groeneveld GJ.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Registered Funding Declared
Hospital pharmacists' opinions on a risk prediction tool for medication-related harm in older people.
Hussain A; Ali K; Davies JG; Stevenson JM; Lippett S; O'Malley M; Parekh N; Rajkumar C.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Registered Funding Declared
Perception, knowledge and attitude towards childhood fever: A survey among final-year medical students.
Milani GP; Corsello A; Fadda M; Falvo I; Giannì ML; Marseglia GL; Cuppari C; Bruzzese E; Bianchetti MG; Schulz PJ; Peroni D; Marchisio P; Chiappini E.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Dose optimization of cefotaxime as pre-emptive treatment in critically ill adult patients: A population pharmacokinetic…
Roelofsen EE; Abdulla A; Muller AE; Endeman H; Gommers D; Dijkstra A; Hunfeld NGM; de Winter BCM; Koch BCP.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Data Funding Declared
A comprehensive pharmacogenomic study indicates roles for SLCO1B1, ABCG2 and SLCO2B1 in rosuvastatin pharmacokinetics.
Lehtisalo M; Taskinen S; Tarkiainen EK; Neuvonen M; Viinamäki J; Paile-Hyvärinen M; Lilius TO; Tapaninen T; Backman JT; Tornio A; Niemi M.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Effect of calcitriol treatment on arterial stiffness in people with type 2 diabetes and stage 3 chronic kidney disease.
Karalliedde J; Fountoulakis N; Corcillo A; Maltese G; Flaquer M; Stathi D; Mangelis A; Panagiotou A; Ayis S; Thomas S; Gnudi L.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential …
Liu F; Aulin LBS; Guo T; Krekels EHJ; Moerland M; van der Graaf PH; van Hasselt JGC.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Data Funding Declared
Primary nonadherence to drugs prescribed by general practitioners: A Dutch database study.
Hempenius M; Rijken S; Groenwold RHH; Hek K; de Boer A; Klungel OH; Gardarsdottir H.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Dose escalations in phase I studies: Feasibility of interpreting blinded pharmacodynamic data.
Hassing GJ; van Esdonk MJ; van Westen GJP; Cohen AF; Burggraaf J; Gal P.
Br J Clin Pharmacol (Unknown)
Published: 2022
2/6 Transparent
Identifying and addressing pill aversion in adults without physiological-related dysphagia: A narrative review.
McCloskey AP; Penson PE; Tse Y; Abdelhafiz MA; Ahmed SN; Lim EJ.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Registered
Influence of tapentadol and oxycodone on the spinal cord and brain using electrophysiology: a randomized, placebo-contr…
Nedergaard RB; Hansen TM; Mørch CD; Niesters M; Dahan A; Drewes AM.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Registered Funding Declared
Interdisciplinary model-informed drug development for extending duration of elagolix treatment in patients with uterine…
Beck D; Winzenborg I; Gao W; Mostafa NM; Chiuve SE; Owens C; Shebley M.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Persistence with urate-lowering therapy in Australia: A longitudinal analysis of allopurinol prescriptions.
Coleshill MJ; Day RO; Tam K; Kouhkamari M; Caillet V; Aung E; Kannangara DRW; Cronin P; Rodgers A; Stocker SL.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Evaluation of the association of anticholinergic burden and delirium in older hospitalised patients - A cohort study co…
Lisibach A; Gallucci G; Benelli V; Kälin R; Schulthess S; Beeler PE; Csajka C; Lutters M.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Volumetric microsampling for simultaneous remote immunosuppressant and kidney function monitoring in outpatient kidney …
Zwart TC; Metscher E; van der Boog PJM; Swen JJ; de Fijter JW; Guchelaar HJ; de Vries APJ; Moes DJAR.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Angiotensin II receptor blockers (ARBs) and manufacturing contamination: A retrospective National Register Study into s…
Salim H; Jones AM.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Barriers and facilitators for the usage of a personal health record for medication reconciliation: A qualitative study …
van der Nat DJ; Huiskes VJB; Taks M; van den Bemt BJF; van Onzenoort HAW.
Br J Clin Pharmacol (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
A review of trial and real-world data applying elements of a realist approach to identify behavioural mechanisms suppor…
Bhattacharya D; Whiteside H; Tang E; Kantilal K; Loke Y; Atkins B; Hill C.
Br J Clin Pharmacol (Unknown)
Published: 2022
4/6 Transparent
Data Funding Declared