Research Papers

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Assessment of Drug Delivery Kinetics to Epidermal Targets In Vivo.
Hoppel M; Tabosa MAM; Bunge AL; Delgado-Charro MB; Guy RH.
AAPS J (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
The Effects of Genetic Mutations and Drugs on the Activity of the Thiamine Transporter, SLC19A2.
Enogieru OJ; Koleske ML; Vora B; Ngo H; Yee SW; Chatad D; Sirota M; Giacomini KM.
AAPS J (Unknown)
Published: 2021
1/6 Transparent
Funding Declared
Inhalable Nanoparticles/Microparticles of an AMPK and Nrf2 Activator for Targeted Pulmonary Drug Delivery as Dry Powder…
Acosta MF; Abrahamson MD; Encinas-Basurto D; Fineman JR; Black SM; Mansour HM.
AAPS J (Unknown)
Published: 2020
1/6 Transparent
Funding Declared
Use of Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Drug-Food Interactions: an Industry Perspec…
Riedmaier AE; DeMent K; Huckle J; Bransford P; Stillhart C; Lloyd R; Alluri R; Basu S; Chen Y; Dhamankar V; Dodd S; Kulkarni P; Olivares-Morales A; Peng CC; Pepin X; Ren X; Tran T; Tistaert C; Heimbach T; Kesisoglou F; Wagner C; Parrott N.
AAPS J (Unknown)
Published: 2020
Between-Batch Bioequivalence (BBE): a Statistical Test to Evaluate In Vitro Bioequivalence Considering the Between-Batc…
Bodin J; Liandrat S; Kocevar G; Petitcolas C.
AAPS J (Unknown)
Published: 2020
Inter-compound and Intra-compound Global Sensitivity Analysis of a Physiological Model for Pulmonary Absorption of Inha…
Melillo N; Grandoni S; Cesari N; Brogin G; Puccini P; Magni P.
AAPS J (Unknown)
Published: 2020
1/6 Transparent
Funding Declared
Item Response Theory Modeling of the International Prostate Symptom Score in Patients with Lower Urinary Tract Symptoms…
Lyauk YK; Jonker DM; Lund TM; Hooker AC; Karlsson MO.
AAPS J (Unknown)
Published: 2020
2/6 Transparent
Funding Declared
Design and Evaluation of a Multiplexed Assay to Assess Human Immunogenicity Against Humira®.
Alleyn M; Closson K; Gentile A; Gulbis N; Taylor C; Rhyne P.
AAPS J (Unknown)
Published: 2020
1/6 Transparent
Funding Declared
Correction to: Remdesivir for Treatment of COVID-19: Combination of Pulmonary and IV Administration May Offer Additiona…
Sun D.
AAPS J (Unknown)
Published: 2020
Saddle-Reset for Robust Parameter Estimation and Identifiability Analysis of Nonlinear Mixed Effects Models.
Bjugård Nyberg H; Hooker AC; Bauer RJ; Aoki Y.
AAPS J (Unknown)
Published: 2020
1/6 Transparent
Funding Declared
A Cautionary Tale: Quantitative LC-HRMS Analytical Procedures for the Analysis of N-Nitrosodimethylamine in Metformin.
Yang J; Marzan TA; Ye W; Sommers CD; Rodriguez JD; Keire DA.
AAPS J (Unknown)
Published: 2020
The Influence of Drug Properties and Ontogeny of Transporters on Pediatric Renal Clearance through Glomerular Filtratio…
Cristea S; Krekels EHJ; Rostami-Hodjegan A; Allegaert K; Knibbe CAJ.
AAPS J (Unknown)
Published: 2020
Remdesivir for Treatment of COVID-19: Combination of Pulmonary and IV Administration May Offer Aditional Benefit.
Sun D.
AAPS J (Unknown)
Published: 2020
Impact of Magnesium Stearate Presence and Variability on Drug Apparent Solubility Based on Drug Physicochemical Propert…
Zarmpi P; Flanagan T; Meehan E; Mann J; Fotaki N.
AAPS J (Unknown)
Published: 2020
1/6 Transparent
Funding Declared
Quality by Design-Based Assessment for Analytical Similarity of Adalimumab Biosimilar HLX03 to Humira®.
Zhang E; Xie L; Qin P; Lu L; Xu Y; Gao W; Wang L; Xie MH; Jiang W; Liu S.
AAPS J (Unknown)
Published: 2020
1/6 Transparent
Machine Learning Analysis of Individual Tumor Lesions in Four Metastatic Colorectal Cancer Clinical Studies: Linking Tu…
Vera-Yunca D; Girard P; Parra-Guillen ZP; Munafo A; Trocóniz IF; Terranova N.
AAPS J (Unknown)
Published: 2020
Development of an Aerosol Dose Collection Apparatus for In Vitro Dissolution Measurements of Orally Inhaled Drug Produc…
Price R; Shur J; Ganley W; Farias G; Fotaki N; Conti DS; Delvadia R; Absar M; Saluja B; Lee S.
AAPS J (Unknown)
Published: 2020
2/6 Transparent
Funding Declared
Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties.
Mudie DM; Samiei N; Marshall DJ; Amidon GE; Bergström CAS.
AAPS J (Unknown)
Published: 2020
1/6 Transparent
Development of In Vitro-In Vivo Correlation for Upadacitinib Extended-Release Tablet Formulation.
Mohamed MF; Trueman S; Othman AA; Othman AA; Han JH; Ju TR; Marroum P.
AAPS J (Unknown)
Published: 2019
2/6 Transparent
Funding Declared
Optimization of Cancer Treatment in the Frequency Domain.
Schulthess P; Rottschäfer V; Yates JWT; van der Graaf PH.
AAPS J (Unknown)
Published: 2019
A Pediatric Covariate Function for CYP3A-Mediated Midazolam Clearance Can Scale Clearance of Selected CYP3A Substrates …
Brussee JM; Krekels EHJ; Calvier EAM; Palić S; Rostami-Hodjegan A; Danhof M; Barrett JS; de Wildt SN; Knibbe CAJ.
AAPS J (Unknown)
Published: 2019
1/6 Transparent
Funding Declared
A Bounded Integer Model for Rating and Composite Scale Data.
Wellhagen GJ; Kjellsson MC; Karlsson MO.
AAPS J (Unknown)
Published: 2019
1/6 Transparent
Funding Declared
A Translational Quantitative Systems Pharmacology Model for CD3 Bispecific Molecules: Application to Quantify T Cell-Me…
Betts A; Haddish-Berhane N; Shah DK; van der Graaf PH; Barletta F; King L; Clark T; Kamperschroer C; Root A; Hooper A; Chen X.
AAPS J (Unknown)
Published: 2019
Variability Attribution for Automated Model Building.
Ibrahim MMA; Nordgren R; Kjellsson MC; Karlsson MO.
AAPS J (Unknown)
Published: 2019
2/6 Transparent
Funding Declared
A Reappraisal of Sedimentation Nonideality Coefficients for the Analysis of Weak Interactions of Therapeutic Proteins.
Chaturvedi SK; Schuck P.
AAPS J (Unknown)
Published: 2019
1/6 Transparent
Funding Declared