Research Papers

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Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA.
Zeaiter N; Belot L; Cunin V; Nahed RA; Tokarska-Schlattner M; Le Gouellec A; Petosa C; Khochbin S; Schlattner U.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
Intermittent rapamycin feeding recapitulates some effects of continuous treatment while maintaining lifespan extension.
Baghdadi M; Nespital T; Monzó C; Deelen J; Grönke S; Partridge L.
Mol Metab (Unknown)
Published: 2024
5/6 Transparent
Data Code Funding Declared
Loss of mitochondrial pyruvate carrier 1 supports proline-dependent proliferation and collagen biosynthesis in ovarian …
Farook MR; Croxford Z; Morgan S; Horlock AD; Holt AK; Rees A; Jenkins BJ; Tse C; Stanton E; Davies DM; Thornton CA; Jones N; Sheldon IM; Vincent EE; Cronin JG.
Mol Metab (Unknown)
Published: 2024
3/6 Transparent
Funding Declared
Insulin at the intersection of thermoregulation and glucose homeostasis.
Winn NC; Schleh MW; Garcia JN; Lantier L; McGuinness OP; Blair JA; Hasty AH; Wasserman DH.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
Treatment of infantile-onset Pompe disease in a rat model with muscle-directed AAV gene therapy.
Muñoz S; Bertolin J; Jimenez V; Jaén ML; Garcia M; Pujol A; Vilà L; Sacristan V; Barbon E; Ronzitti G; El Andari J; Tulalamba W; Pham QH; Ruberte J; VandenDriessche T; Chuah MK; Grimm D; Mingozzi F; Bosch F.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
β-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice.
Suda N; Bartolomé A; Liang J; Son J; Yagishita Y; Siebel C; Accili D; Ding H; Pajvani UB.
Mol Metab (Unknown)
Published: 2024
3/6 Transparent
Funding Declared
Human ACVR1C missense variants that correlate with altered body fat distribution produce metabolic alterations of grade…
Tangseefa P; Jin H; Zhang H; Xie M; Ibáñez CF.
Mol Metab (Unknown)
Published: 2024
3/6 Transparent
Funding Declared
Identification of AgRP cells in the murine hindbrain that drive feeding.
Bachor TP; Hwang E; Yulyaningsih E; Attal K; Mifsud F; Pham V; Vagena E; Huarcaya R; Valdearcos M; Vaisse C; Williams KW; Emmerson PJ; Xu AW.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
Hepatic regulator of G protein signaling 14 ameliorates NAFLD through activating cAMP-AMPK signaling by targeting Giα1/…
Wang J; Guo Y; He Y; Qin Y; Li X; Yang L; Liu K; Xiao L.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
TAAR1 agonists improve glycemic control, reduce body weight and modulate neurocircuits governing energy balance and fee…
Dedic N; Wang L; Hajos-Korcsok E; Hecksher-Sørensen J; Roostalu U; Vickers SP; Wu S; Anacker C; Synan C; Jones PG; Milanovic S; Hopkins SC; Bristow LJ; Koblan KS.
Mol Metab (Unknown)
Published: 2024
3/6 Transparent
Funding Declared
Permanent neonatal diabetes-causing insulin mutations have dominant negative effects on beta cell identity.
Zhang Y; Sui L; Du Q; Haataja L; Yin Y; Viola R; Xu S; Nielsson CU; Leibel RL; Barbetti F; Arvan P; Egli D.
Mol Metab (Unknown)
Published: 2024
3/6 Transparent
Funding Declared
RIPK3 promotes islet amyloid-induced β-cell loss and glucose intolerance in a humanized mouse model of type 2 diabetes.
Mukherjee N; Contreras CJ; Lin L; Colglazier KA; Mather EG; Kalwat MA; Esser N; Kahn SE; Templin AT.
Mol Metab (Unknown)
Published: 2024
3/6 Transparent
Funding Declared
Long non-coding RNA LncCplx2 regulates glucose homeostasis and pancreatic β cell function.
Wang L; Hu L; Wang X; Geng Z; Wan M; Hao J; Liu H; Fan Y; Xu T; Li Z.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
Antibody blockade of activin type II receptors preserves skeletal muscle mass and enhances fat loss during GLP-1 recept…
Nunn E; Jaiswal N; Gavin M; Uehara K; Stefkovich M; Drareni K; Calhoun R; Lee M; Holman CD; Baur JA; Seale P; Titchenell PM.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
Programming of cardiac metabolism by miR-15b-5p, a miRNA released in cardiac extracellular vesicles following ischemia-…
Pantaleão LC; Loche E; Fernandez-Twinn DS; Dearden L; Córdova-Casanova A; Osmond C; Salonen MK; Kajantie E; Niu Y; de Almeida-Faria J; Thackray BD; Mikkola TM; Giussani DA; Murray AJ; Bushell M; Eriksson JG; Ozanne SE.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
NF1 deficiency drives metabolic reprogramming in ER+ breast cancer.
House RRJ; Tovar EA; Redlon LN; Essenburg CJ; Dischinger PS; Ellis AE; Beddows I; Sheldon RD; Lien EC; Graveel CR; Steensma MR.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
ATP7A-dependent copper sequestration contributes to termination of β-CATENIN signaling during early adipogenesis.
Yang H; Kabin E; Dong Y; Zhang X; Ralle M; Lutsenko S.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
Adipose knockout of H-ferritin improves energy metabolism in mice.
Lu B; Guo S; Zhao J; Wang X; Zhou B.
Mol Metab (Unknown)
Published: 2024
3/6 Transparent
Funding Declared
Two-step regulation by matrix Gla protein in brown adipose cell differentiation.
Zhang L; Cai X; Ma F; Qiao X; Ji J; Ma JA; Vergnes L; Zhao Y; Yao Y; Wu X; Boström KI.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
A viral insulin-like peptide inhibits IGF-1 receptor phosphorylation and regulates IGF1R gene expression.
Chrudinová M; Kirk NS; Chuard A; Venugopal H; Zhang F; Lubos M; Gelfanov V; Páníková T; Žáková L; Cutone J; Mojares M; DiMarchi R; Jiráček J; Altindis E.
Mol Metab (Unknown)
Published: 2024
4/6 Transparent
Data Funding Declared
Sestrin2 maintains hepatic immune homeostasis and redox balance partially via inhibiting RIPK3-mediated necroptosis in …
Zhang JB; Zhang QR; Jin Q; Yang J; Lin SZ; Fan JG.
Mol Metab (Unknown)
Published: 2023
3/6 Transparent
Funding Declared
Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Akhmetshina A; Bianco V; Bradić I; Korbelius M; Pirchheim A; Kuentzel KB; Eichmann TO; Hinteregger H; Kolb D; Habisch H; Liesinger L; Madl T; Sattler W; Radović B; Sedej S; Birner-Gruenberger R; Vujić N; Kratky D.
Mol Metab (Unknown)
Published: 2023
4/6 Transparent
Data Funding Declared
Developmental metformin exposure does not rescue physiological impairments derived from early exposure to altered mater…
Cantacorps L; Zhu J; Yagoub S; Coull BM; Falck J; Chesters RA; Ritter K; Serrano-Lope M; Tscherepentschuk K; Kasch LS; Paterson M; Täger P; Baidoe-Ansah D; Pandey S; Igual-Gil C; Braune A; Lippert RN.
Mol Metab (Unknown)
Published: 2023
3/6 Transparent
Funding Declared
Molecular profiling of high-level athlete skeletal muscle after acute endurance or resistance exercise - A systems biol…
Reitzner SM; Emanuelsson EB; Arif M; Kaczkowski B; Kwon AT; Mardinoglu A; Arner E; Chapman MA; Sundberg CJ.
Mol Metab (Unknown)
Published: 2023
5/6 Transparent
Data Code Funding Declared
Activation of a non-neuronal cholinergic system in visceral white adipose tissue of obese mice and humans.
Severi I; Perugini J; Ruocco C; Coppi L; Pedretti S; Di Mercurio E; Senzacqua M; Ragni M; Imperato G; Valerio A; Mitro N; Crestani M; Nisoli E; Giordano A.
Mol Metab (Unknown)
Published: 2023
3/6 Transparent
Funding Declared