Research Papers

25 of 163 papers

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A dual role of lysophosphatidic acid type 2 receptor (LPAR2) in nonsteroidal anti-inflammatory drug-induced mouse enter…
Hutka B; Várallyay A; László SB; Tóth AS; Scheich B; Paku S; Vörös I; Pós Z; Varga ZV; Norman DD; Balogh A; Benyó Z; Tigyi G; Gyires K; Zádori ZS.
Acta Pharmacol Sin (Unknown)
Published: 2023
4/6 Transparent
Code Funding Declared
Neuronal K<sup>+</sup>-Cl<sup>-</sup> cotransporter KCC2 as a promising drug target for epilepsy treatment.
McMoneagle E; Zhou J; Zhang S; Huang W; Josiah SS; Ding K; Wang Y; Zhang J.
Acta Pharmacol Sin (Unknown)
Published: 2023
3/6 Transparent
Funding Declared
Cynaropicrin disrupts tubulin and c-Myc-related signaling and induces parthanatos-type cell death in multiple myeloma.
Boulos JC; Omer EA; Rigano D; Formisano C; Chatterjee M; Leich E; Klauck SM; Shan LT; Efferth T.
Acta Pharmacol Sin (Unknown)
Published: 2023
3/6 Transparent
Funding Declared
Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors.
Kovács SA; Fekete JT; Győrffy B.
Acta Pharmacol Sin (Unknown)
Published: 2023
4/6 Transparent
Data Funding Declared
GPR84 regulates pulmonary inflammation by modulating neutrophil functions.
Wang SW; Zhang Q; Lu D; Fang YC; Yan XC; Chen J; Xia ZK; Yuan QT; Chen LH; Zhang YM; Nan FJ; Xie X.
Acta Pharmacol Sin (Unknown)
Published: 2023
3/6 Transparent
Funding Declared
Quinpirole ameliorates nigral dopaminergic neuron damage in Parkinson's disease mouse model through activating GHS-R1a/…
Tang TT; Bi MX; Diao MN; Zhang XY; Chen L; Xiao X; Jiao Q; Chen X; Yan CL; Du XX; Jiang H.
Acta Pharmacol Sin (Unknown)
Published: 2023
3/6 Transparent
Funding Declared
Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interact…
Ma YH; Hong X; Wu F; Xu XF; Li R; Zhong J; Zhou YQ; Liu SW; Zhan J; Xu W.
Acta Pharmacol Sin (Unknown)
Published: 2023
3/6 Transparent
Funding Declared
MANF ameliorates DSS-induced mouse colitis via restricting Ly6C<sup>hi</sup>CX3CR1<sup>int</sup> macrophage transformat…
Yang L; Shen WW; Shao W; Zhao Q; Pang GZ; Yang Y; Tao XF; Zhang WP; Mei Q; Shen YX.
Acta Pharmacol Sin (Unknown)
Published: 2023
4/6 Transparent
Data Funding Declared
Multi-compound and drug-combination pharmacokinetic research on Chinese herbal medicines.
Li C; Jia WW; Yang JL; Cheng C; Olaleye OE.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Mesenchymal stem cells in fibrotic diseases-the two sides of the same coin.
Qin L; Liu N; Bao CL; Yang DZ; Ma GX; Yi WH; Xiao GZ; Cao HL.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adu…
Shi CJ; Lian JJ; Zhang BW; Cha JX; Hua QH; Pi XP; Hou YJ; Xie X; Zhang R.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376.
Luan XD; Chen BX; Shang WJ; Yin WC; Jin Y; Zhang LK; Xu HE; Zhang SY.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrop…
Zha ZX; Lin Y; Wang KX; Zhang YL; Li D; Xu GQ; Xu QM; Liu YL.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Transcriptional regulation and small compound targeting of ACE2 in lung epithelial cells.
Liang LJ; Wang D; Yu H; Wang J; Zhang H; Sun BB; Yang FY; Wang Z; Xie DW; Feng RE; Xu KF; Wang GZ; Zhou GB.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Safety, tolerability, and pharmacokinetics of VV116, an oral nucleoside analog against SARS-CoV-2, in Chinese healthy s…
Qian HJ; Wang Y; Zhang MQ; Xie YC; Wu QQ; Liang LY; Cao Y; Duan HQ; Tian GH; Ma J; Zhang ZB; Li N; Jia JY; Zhang J; Aisa HA; Shen JS; Yu C; Jiang HL; Zhang WH; Wang Z; Liu GY.
Acta Pharmacol Sin (Unknown)
Published: 2022
4/6 Transparent
Registered Funding Declared
FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice.
Zhu DY; Lu J; Xu R; Yang JZ; Meng XR; Ou-Yang XN; Yan QY; Nie RF; Zhao T; Chen YD; Lu Y; Zhang YN; Li WJ; Shen X.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases.
Lin MM; Liu N; Qin ZH; Wang Y.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
Structure genomics of SARS-CoV-2 and its Omicron variant: drug design templates for COVID-19.
Wu CR; Yin WC; Jiang Y; Xu HE.
Acta Pharmacol Sin (Unknown)
Published: 2022
3/6 Transparent
Funding Declared
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury.
Xie ZY; Dong W; Zhang L; Wang MJ; Xiao ZM; Zhang YH; Shi WX; Huang Y; Yang Y; Li CL; Fu L; Zhao XC; Li RZ; Li ZL; Chen YH; Ye ZM; Liu SX; Dong Z; Liang XL.
Acta Pharmacol Sin (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
GPR84 signaling promotes intestinal mucosal inflammation via enhancing NLRP3 inflammasome activation in macrophages.
Zhang Q; Chen LH; Yang H; Fang YC; Wang SW; Wang M; Yuan QT; Wu W; Zhang YM; Liu ZJ; Nan FJ; Xie X.
Acta Pharmacol Sin (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
Ferroptosis in viral infection: the unexplored possibility.
Wang MP; Joshua B; Jin NY; Du SW; Li C.
Acta Pharmacol Sin (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
SARS-CoV-2 receptor binding domain radio-probe: a non-invasive approach for angiotensin-converting enzyme 2 mapping in …
Li D; Ding J; Liu TL; Wang F; Meng XX; Liu S; Yang Z; Zhu H.
Acta Pharmacol Sin (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
Prenatal inflammation exposure-programmed hypertension exhibits multi-generational inheritance via disrupting DNA methy…
Guan X; Dan GR; Yang Y; Ji Y; Lai WJ; Wang FJ; Meng M; Mo BH; Huang P; You TT; Deng YF; Song L; Guo W; Yi P; Yu JH; Gao Y; Shou WN; Chen BB; Deng YC; Li XH.
Acta Pharmacol Sin (Unknown)
Published: 2021
3/6 Transparent
Data Funding Declared
Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrop…
Song MY; Wang JX; Sun YL; Han ZF; Zhou YT; Liu Y; Fan TH; Li ZG; Qi XM; Luo Y; Yang PR; Li BC; Zhang XR; Wang J; Wang C.
Acta Pharmacol Sin (Unknown)
Published: 2021
2/6 Transparent
Funding Declared
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein.
Wang L; Wu Y; Yao S; Ge H; Zhu Y; Chen K; Chen WZ; Zhang Y; Zhu W; Wang HY; Guo Y; Ma PX; Ren PX; Zhang XL; Li HQ; Ali MA; Xu WQ; Jiang HL; Zhang LK; Zhu LL; Ye Y; Shang WJ; Bai F.
Acta Pharmacol Sin (Unknown)
Published: 2021
3/6 Transparent
Funding Declared