Identification of the gene encoding Brain Cell Membrane Protein 1 (BCMP1), a putative four-transmembrane protein distantly related to the Peripheral Myelin Protein 22 / Epithelial Membrane Proteins and the Claudins.

"as in the interval an updated homologous mouse sequence had been deposited in the database (clone mncb-0941 embl/genbank acc #: ab041540) the comparison of both sequences revealed that the coding region was entirely conserved in dog and mouse (fig 2 ).; the human est sequence dkfzp564e153 (embl/genbank acc #: al049257) that corresponds to the 3' utr of dog bcmp1 mrna had been localized on chromosome x the corresponding human genomic sequence could not be found by blast searches against sequences available in the database."

"AcknowledgementsWe thank Drs J.E. Dumont and G. Vassart for their continuous support and critical interest in our work. We are indebted to C. Govaerts for sequence alignments and phylogenetic tree construction, to the technicians of the Service de Génétique Médicale de l'Hôpital Erasme for the realization of DNA sequencing runs and to P. Van Vooren for technical help. This work was supported by the Belgian program "Poles d'Attraction Interuniversitaire" (Prime Minister's Office, Science Policy Programming) and the Fonds National de la Recherche Scientifique (FNRS, FRSM). R.G. is supported by funds from the CNRS and American Kennel Club. C.S. and D.C. are Research Directors of the FNRS."