Origins of chromosomal rearrangement hotspots in the human genome: evidence from the AZFa deletion hotspots.

"fasta format (additional data file 2"

"monte carlo (stochastic) simulations were written in interactive data language 5 3 (research systems) by m e h (source code is available in additional data file 3).; additional data available with the online version of this paper comprise: additional data file 1 a table of primers used in amplifying and sequencing the azfa -hervs (additional data file 1 ); additional data file 2 the alignment of proximal and distal azfa -hervs from human chimpanzee and gorilla in fasta format (additional data file 2 ); and additional data file 3 the source code for simulations of gene conversion used in this study written in interactive data language (idl)(additional data file 3 )."

"AcknowledgementsWe thank Mark Jobling and Elena Bosch for discussions and sharing research materials, and are grateful to Mike Jackson for comments on an earlier manuscript. We are also grateful to Jane Rogers for her support. This work was supported by the McDonald Institute and the Wellcome Trust Sanger Institute."