Reduced repair capacity of a DNA clustered damage site comprised of 8-oxo-7,8-dihydro-2'-deoxyguanosine and 2-deoxyribonolactone results in an increased mutagenic potential of these lesions.

Journal Information

Full Title: Mutat Res

Abbreviation: Mutat Res

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
2/6
0.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"Conflict of interest statement The authors declare that there are no conflicts of interest."

Evidence found in paper:

"We thank Mr. Vandan Shah for synthesizing the oligonucleotides containing NI. MMG is grateful to the National Institute of General Medical Science (GM-063028) for support. The work of S.C., P. ON, and M.E.L. was supported by the Medical Research Council, UK, grant MC_PC_12001."

Protocol Registration
Open Access
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025