The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency.

Authors:
Brüsehafer K; Manshian BB; Doherty AT; Zaïr ZM; Johnson GE and 2 more

Journal:
Mutagenesis

Publication Year: 2015

DOI:
10.1093/mutage/gev069

PMCID:
PMC4748179

PMID:
26362870

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Journal Information

Full Title: Mutagenesis

Abbreviation: Mutagenesis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Environmental Health

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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"Conflict of interest statement: None declared."

Evidence found in paper:

"Funding This study was supported by a Collaborative Award in Science and Engineering (CASE) studentship from Medical Research Council (MRC, grant number: G0900840-1/1) and AstraZeneca."

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Last Updated: Aug 05, 2025