Validation of the 3D reconstructed human skin Comet assay, an animal-free alternative for following-up positive results from standard in vitro genotoxicity assays.

Authors:
Pfuhler S; Pirow R; Downs TR; Haase A; Hewitt N and 6 more

Journal:
Mutagenesis

Publication Year: 2021

DOI:
10.1093/mutage/geaa009

PMCID:
PMC8081376

PMID:
32152633

Journal Information

Full Title: Mutagenesis

Abbreviation: Mutagenesis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Environmental Health

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
2/6
0.0% Transparent
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Evidence found in paper:

"Conflict of interest statement: Kerstin Reisinger is an employee of the company which developed and commercializes the Phenion® Full-Thickness Skin Tissue. None of the other authors report a conflict of interest."

Evidence found in paper:

"The work was financially supported by the Federal Ministry of Education and Research (German: Bundesministerium für Bildung und Forschung) (grant Nos. 0315226, 0316008) and by Cosmetics Europe – The Personal Care Association."

Protocol Registration
Open Access
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Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025