Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients.

"all data are shown as mean ? sd. table 2"

"Competing interests The authors declare no competing interests."

"The authors sincerely thank Prof. Zi-he Rao and Prof. Hai-tao Yang for kindly providing the initial protein sample as well as substrate for the enzymatic assay of 3CLpro. We also thank the staff from beamlines BL17U1 and BL18U1 at Shanghai Synchrotron Radiation Facility. This work was supported by the National Key R&D Program of China (nos. 2020YFC0841400, 2017YFB0202604, and 2016YFA0502301), the National Natural Science Foundation of China (nos. 91953000 and 21877122), the International Partnership Program of Chinese Academy of Sciences (no. 153631KYSB20170043), Chinese Academy of Engineering and Jack Ma Foundation (no. 2020-CMKYGG-05), and Science and Technology Commission of Shanghai Municipality (no. 20431900200)."