A large-scale genome-lipid association map guides lipid identification.
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Full Title: Nat Metab
Abbreviation: Nat Metab
Country: Unknown
Publisher: Unknown
Language: N/A
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"snp associations were performed using the scan1snps() function in r/qtl2_0 20 accessing variants from the database cc_variants sqlite (available here: https://ndownloader figshare com/files/18533342 ) and genes from mouse_genes_mgi sqlite (available here: https://ndownloader figshare com/files/17609252 ) via r/rsqlite_2 1 2.; genotypes and additional phenotype data associated with the do mouse population have been deposited with dryad (doi: 10 5061/dryad pj105 ; data files: attie islet eqtl data) (see keller et al 2018 for details).; snp associations were performed accessing variants from the database cc_variants sqlite (available here: https://ndownloader figshare com/files/18533342 ) and genes from mouse_genes_mgi sqlite (available here: https://ndownloader figshare com/files/17609252 ). code for data analysis and plotting is available at https://github com/vanilink/dolipids/ with input from supplementary tables8 and 9 ."
"code for data analysis and plotting is available at https://github com/vanilink/dolipids/ with input from supplementary tables8 and 9 . code for data analysis and plotting is available at https://github com/vanilink/dolipids/ with input from supplementary tables8 and 9 ."
"Competing Interest Statement: The authors declare that they have no conflicts of interest with the contents of this article."
"This work was supported by National Institutes of Health Grants P41 GM108538 and 2R01DK101573. This research was performed using the compute resources and assistance of the UW-Madison Center For High Throughput Computing (CHTC) in the Department of Computer Sciences. The CHTC is supported by UW-Madison, the Advanced Computing Initiative, the Wisconsin Alumni Research Foundation, the Wisconsin Institutes for Discovery, and the National Science Foundation, and is an active member of the Open Science Grid, which is supported by the National Science Foundation and the U.S. Department of Energy’s Office of Science. We thank B. Paulson for help with sample preparation and D. Hwang for help with figures. We thank J. Simcox (Department of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA) for providing the His-tagged CMV6-GFP plasmid and Hepa1-6 cells."
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