Gut microbiome pattern reflects healthy ageing and predicts survival in humans.

Publication Year: 2021

DOI:
10.1038/s42255-021-00348-0

PMCID:
PMC8169080

PMID:
33619379

Journal Information

Full Title: Nat Metab

Abbreviation: Nat Metab

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Metabolism

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Evidence found in paper:

"asv abundances from the american gut project were obtained from the 125bp biom table deposited in figshare [6137192] provided in the original manuscript by mcdonald et al .; metadata for study participants was obtained from the table provided in the same publication and also deposited in figshare [6137315] .; the american gut project biom table and the accompanying metadata is publicly available through figshare reference numbers [6137192] 49 and [6137192] 50 respectively."

Evidence found in paper:

"code availability: code used to process gut microbiome samples is available on the gibbons lab github page ( https://github com/gibbons-lab/mbtools ) and code used for statistical analysis is available through the hood-price lab github ( https://github com/pricelab/agingmicrobiome )."

Evidence found in paper:

"Competing interests: The authors declare no competing interests."

Evidence found in paper:

"Funding: This work was supported by the M.J. Murdock Charitable Trust (L.H. and N.D.P.), Arivale and a generous gift from C. Ellison. S.M.G., C.D. and S.P. were supported by a Washington Research Foundation Distinguished Investigator Award and by start-up funds from the Institute for Systems Biology. Further support comes from the National Academy of Medicine Catalyst Award (N.D.P., S.M.G., L.H., E.S.O.) and NIH grant U19AG023122 awarded by the National Institute on Aging (NIA). The Osteoporotic Fractures in Men (MrOS) Study is supported by National Institutes of Health funding. The following institutes provide support: the NIA, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the National Center for Advancing Translational Sciences (NCATS), and NIH Roadmap for Medical Research under the following grant numbers: U01 AG027810, U01 AG042124, U01 AG042139, U01 AG042140, U01 AG042143, U01 AG042145, U01 AG042168, U01 AR066160, and UL1 TR000128. NIAMS grant R01AR061445 provided support for the generation of 16S genotyping data."

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Last Updated: Aug 05, 2025