The impact of sequencing depth on the inferred taxonomic composition and AMR gene content of metagenomic samples.

"availability of data and materials the datasets generated and/or analysed during the current study are available in the ncbi repository (bioproject number: prjna529503). availability of data and materials the datasets generated and/or analysed during the current study are available in the ncbi repository (bioproject number: prjna529503"

"Competing interests The authors declare that they have no competing interests."

"Funding This work was funded by the Antimicrobial Resistance Cross-council Initiative supported by the seven research councils [NE/N019989/1 and NE/N019660/1]. DWC, TEAP, and ASW are affiliated to the National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England (PHE) [grant HPRU-2012-10041]. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, the Department of Health or Public Health England. This work is supported by the NIHR Oxford Biomedical Research Centre. The funders had no role in the design of the study, analyses, interpretation of the data or writing of the manuscript."