Disparate Regions of the Human Chemokine CXCL10 Exhibit Broad-Spectrum Antimicrobial Activity against Biodefense and Antibiotic-Resistant Bacterial Pathogens.

Authors:
Crawford MA; Ward AE; Gray V; Bailer P; Fisher DJ and 9 more

Journal:
ACS Infect Dis

Publication Year: 2022

DOI:
10.1021/acsinfecdis.2c00456

PMCID:
PMC9841529

PMID:
36475632

Journal Information

Full Title: ACS Infect Dis

Abbreviation: ACS Infect Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Anti-Infective Agents

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"The authors declare no competing financial interest."

Evidence found in paper:

"The authors thank Katie R. Margulieux and Arpita Singh (University of Virginia) for assistance with preliminary studies, Nixon M. Crawford (Charlottesville, VA) for generating scrambled peptide sequences, Erum Khan (Aga Khan University) for providing clinical isolates, and Christine Lascols (CDC) for performing antimicrobial susceptibility testing. This research was supported by The Ivy Foundation and Global Infectious Diseases Institute at the University of Virginia, and by the National Institute of Allergy and Infectious Diseases Grant R01 AI150941. Additional support for this work was received from the National Institutes of Health Fellowship F30 HD101348 and Training Grants T32 GM007267 and T32 GM080186 (A.E.W.), as well as Grants R01 AI30557 (L.K.T.) and R01 AI097312 (M.C.G. and A.K.C.). The Table of Contents graphic was created with BioRender.com."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025