Systems genetics identifies miRNA-mediated regulation of host response in COVID-19.

"the mirna data is deposited in geo under accession gse220077.; the mrna data is deposited in geo under accession gse220076.; availability of data and materials the mirna data is deposited in geo under accession gse220077 and the mrna data is deposited in geo under accession gse220076. all code and phenotype data used for analyses is available at https://github com/yidaghdour/covid-mirna . availability of data and materials the mirna data is deposited in geo under accession gse220077"

"all code and phenotype data used for analyses is available at https://github com/yidaghdour/covid-mirna ."

"Declarations Ethics approval and consent to participateThe blood samples and clinical records were obtained from Al Ain Hospital, Al Rahba Hospital, Mafraq Hospital and Sheikh Khalifa Medical Center in Abu Dhabi, United Arab Emirates. All patients signed an informed consent to participate in the study before sample donation. The study was reviewed and approved by the Research Ethics Committee at New York University Abu Dhabi (NYUAD) (HRPP-2020-59) and the Abu Dhabi COVID-19 Research International Review Board Committee of the Department of Health (Ref no: DOH/CVDC/2020/874). This study was conducted in accordance with the principles of the Helsinki Declaration. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"We would like to thank all the patients who participated in this study. We thank all the individuals who facilitated sample collection and clinical work across multiple hospitals, and in particular the nurses. This project is supported by NYUAD grant AD105 to Youssef Idaghdour, and a NYUAD Postgraduate Research Fellowship to Tamara Gjorgjieva. Author contributions: Conceptualization, Y.I., H.Al., T.G.; Methodology, A.C., T.S., M.Al., O.B., M.A.A., J.D.M., G.B., M.M.D, C.L., M.Ar., A.L., S.Y.S, J.A.; Formal Analysis, T.G., A.C.; Resources, Y.I., K.G., F.P., R.A., A.K., A.A., H. Ab.; Data Curation, V.M. T.G.; Writing—Original draft preparation, T.G., A.C., Y.I.; Writing—Review & Editing, T.G., Y.I., A.C., T.S.; Data Visualization, T.G.; Supervision, Y.I., H.Al., K.G., F.P., G.E., H.D.; Project Administration, Y.I.; Funding Acquisition, Y.I. All authors read and approved the final manuscript."