Clonal expansion and rapid characterization of <i>Klebsiella pneumoniae</i> ST1788, an otherwise uncommon strain spreading in Wales, UK.

"esbl kl2 klebsiella pneumoniae multidrug resistance pcr st1788 yersiniabactin openaccessembargo 0 genome data generated and/or analysed in this work are available in the european nucleotide archive (ena) under project number erp135832 or prjeb48990.; short read data were made available on the european nucleotide archive (ena) under project accession erp135832; short read data for the 43 st1788 strains previously sequenced are also available on the ena under project accession prjeb48990.; in this clade also there is evidence of wider geographical spread of strains as it includes three isolates from three patients admitted to hospital h or hospital k located in south east wales with no admission history to hospitals a or i finally interspersed within this clade are 11 strains isolated from eight patients attending general practices located both in south east and south west wales; four of these strains were from four patients with no history of admission to hospital a or hospital i during this study a new bla shv variant and a new bla ctx-m variant were identified; these variants were submitted to genbank and later designated as bla shv-232 (accession or224963) and bla ctx-m-266 (accession or224962)."

"Conflicts of interest The authors declare no conflicts of interest."

"Funding information S.D. is supported by funding from the Centre for Genomic Pathogen Surveillance and the Bill and Melinda Gates Foundation (investment no. INV-025280). Illumina sequencing was funded as part of the Antimicrobial Resistance and Genomic Typing Project (ARGENT) by the Welsh Assembly Government."