GoM DE: interpreting structure in sequence count data with differential expression analysis allowing for grades of membership.

"the data sets supporting the conclusions of this article are available in zenodo repositories [ 186 187 ]. availability of data and materials the fasttopics r package is available on github ( https://github com/stephenslab/fasttopics ) and cran ( https://cran r-project org/package=fasttopics ). table s1 in [ ]). the full data set"

"availability of data and materials the fasttopics r package is available on github ( https://github com/stephenslab/fasttopics ) and cran ( https://cran r-project org/package=fasttopics ).; a seurat wrapper for fasttopics is available from https://github com/stephenslab/seurat-wrappers ."

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was supported by the NHGRI at the National Institutes of Health under award number 5R01HG002585."