Precision pharmacological reversal of strain-specific diet-induced metabolic syndrome in mice informed by epigenetic and transcriptional regulation.

"plos publication stage vor-update-to-uncorrected-proof publication update 2023-11-02 data availability all wgbs and rna-seq sequencing reads cpg reports and gene abundances are available at the ncbi gene expression omnibus: gse215954.; data availability all wgbs and rna-seq sequencing reads cpg reports and gene abundances are available at the ncbi gene expression omnibus: gse215954. s1 table macronutrient and lipid compositions of the standard and american diets (xlsx data availability all wgbs and rna-seq sequencing reads cpg reports and gene abundances are available at the ncbi gene expression omnibus: gse215954"

"The authors have declared that no competing interests exist."

"This work was funded by NIH grants RM1HG008529 (to A.P.F. and D.W.T.), DP1DK119129 (to A.P.F.), and R01DK130333 (to D.W.T.). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."