Integrated Transcriptomic and Metabolomic Mapping Reveals the Mechanism of Action of Ceftazidime/Avibactam against Pan-Drug-Resistant <i>Klebsiella pneumoniae</i>.

Authors:
Hussein M; Allobawi R; Zhao J; Yu H; Neville SL and 7 more

Journal:
ACS Infect Dis

Publication Year: 2023

DOI:
10.1021/acsinfecdis.3c00264

PMCID:
PMC10714405

PMID:
37878861

Journal Information

Full Title: ACS Infect Dis

Abbreviation: ACS Infect Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Anti-Infective Agents

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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5/6
83.3% Transparent
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Evidence found in paper:

"data availability statement the data supporting the findings of this study are available in the supplementary materials and the raw data and analysis scripts are deposited in a publicly accessible repository genbank and the sequence read archive (sra) accession number prjna1035254."

Evidence found in paper:

"data availability statement the data supporting the findings of this study are available in the supplementary materials and the raw data and analysis scripts are deposited in a publicly accessible repository genbank and the sequence read archive (sra) accession number prjna1035254. data availability statement the data supporting the findings of this study are available in the supplementary materials and the raw data and analysis scripts are deposited in a publicly accessible repository genbank and the sequence read archive (sra) accession number prjna1035254."

Evidence found in paper:

"The authors declare no competing financial interest."

Evidence found in paper:

"J.L. is an Australian National Health and Medical Research Council (NHMRC) Principal Research Fellow, and T.V. is an Australian REDI MPT Connect Fellow. J.Z. is a recipient of the 2022 Faculty of Medicine, Nursing and Health Sciences Bridging Fellowship, Monash University. G.G.R., T.V., and J.L. were supported by the National Institute of Allergy and Infectious Diseases, award numbers R01AI146241 and R01AI170889. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025