The clinical, genomic, and microbiological profile of invasive multi-drug resistant <i>Escherichia coli</i> in a major teaching hospital in the United Kingdom.

"Conflicts of interest All authors declare no conflicts of interest."

"Funding information W.L.H. is funded by a National Institute for Health and Care Research (NIHR) Clinical Lecturer position with the University of Cambridge. B.W. was funded from the National Institute for Health Research Cambridge Biomedical Research Centre at the Cambridge University Hospitals NHS Foundation Trust. M.E.T. was supported by a Clinician Scientist Fellowship (funded by the Academy of Medical Sciences and The Health Foundation), and the National Institute for Health Research Cambridge Biomedical Research Centre. Stephen Baker has a Wellcome senior research fellowship (215515/Z/19/Z). The Wellcome Sanger Institute is supported by a Wellcome core grant (220540/Z/20/A). The funders had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication."