Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs.

Publication Year: 2023

DOI:
10.1371/journal.pgen.1011014

PMCID:
PMC10637723

PMID:
37906604

Journal Information

Full Title: PLoS Genet

Abbreviation: PLoS Genet

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"the raw data from the atf4-293 gene expression experiment is available at the arrayexpress repository (accession number e-mtab-3318).; the raw sequencing data is available at ncbi geo under the accession gse225216. promoter regions were defined as tss +/- 1kb (gencode v38) (xlsx) click here for additional data file s1 data (xlsx) click here for additional data file. file s1 table (xlsx"

Code Sharing
Evidence found in paper:

"The authors have declared that no competing interests exist."

Evidence found in paper:

"This work was supported by the Estonian Research Council (Eesti Teadusagentuur) grants PRG1475 (to TÖ), PUT269 (to TÖ) and IUT34-4 (to PA) and European Molecular Biology Laboratory grant VLTAT18559 (to PA). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025