Spt5 C-terminal repeat domain phosphorylation and length negatively regulate heterochromatin through distinct mechanisms.

"yours sincerely sigurd braun phd guest editor plos genetics wendy bickmore section editor plos genetics www plosgenetics org twitter: @plosgenetics ---------------------------------------------------- comments from the reviewers (if applicable): ---------------------------------------------------- data deposition if you have submitted a research article or front matter that has associated data that are not suitable for deposition in a subject-specific public repository (such as genbank or arrayexpress) one way to make that data available is to deposit it in the dryad digital repository .; journalid=pgenetics&manu=pgenetics-d-22-01223r2 more information about depositing data in dryad is available at http://www datadryad org/depositing ."

"The authors have declared that no competing interests exist."

"This work was funded by the Canadian Institutes of Health Research (https://cihr-irsc.gc.ca/)(MOP-130362 and PJT-173356 to J.C.T.) and the Natural Sciences and Engineering Research Council (https://www.nserc-crsng.gc.ca/)(RGPIN 03661-15 and RGPIN-2020-05174 to J.C.T.). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."