The burden of rare variants in DPYS gene is a novel predictor of the risk of developing severe fluoropyrimidine-related toxicity.

Authors:
De Mattia E; Polesel J; Silvestri M; Roncato R; Scarabel L and 5 more

Journal:
Hum Genomics

Publication Year: 2023

DOI:
10.1186/s40246-023-00546-9

PMCID:
PMC10633914

PMID:
37946254

View on PubMed View on PMC View Publisher
Journal Information

Full Title: Hum Genomics

Abbreviation: Hum Genomics

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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"Declarations Ethics approval and consent to participateSee the “Patient cohorts and Clinical Data Collection” section. Consent for publicationNot applicable. Competing interestsThe authors declare no conflict of interest. Competing interests The authors declare no conflict of interest."

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"Funding This work was supported by the Italian Ministry of Health (Ricerca Corrente)."

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Last Updated: Aug 05, 2025