Activation of PXR causes drug interactions with Paxlovid in transgenic mice.

Authors:
Lei S; Guo A; Lu J; Qi Q; Devanathan AS and 2 more

Journal:
Acta Pharm Sin B

Publication Year: 2023

DOI:
10.1016/j.apsb.2023.08.001

PMCID:
PMC10638548

PMID:
37969744

View on PubMed View on PMC View Publisher
Journal Information

Full Title: Acta Pharm Sin B

Abbreviation: Acta Pharm Sin B

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology & Pharmacy

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Evidence found in paper:

"Conflicts of interest The authors declare no conflicts of interest."

Evidence found in paper:

"This study was supported in part by the 10.13039/100008460National Center for Complementary and Integrative Health (R21AT011088, USA), the 10.13039/100000062National Institute of Diabetes and Digestive and Kidney Diseases (R01DK126875, USA), and the 10.13039/100000060National Institute of Allergy and Infectious Diseases (R01AI131983, USA). Phoenix WinNonlin was generously provided to the University of Pittsburgh School of Pharmacy by Certara, Inc., through the Center of Excellence Program for academic institutions."

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Last Updated: Aug 05, 2025