TGFß/activin-dependent activation of Torso controls the timing of the metamorphic transition in the red flour beetle Tribolium castaneum.

"yours sincerely lynn m riddiford academic editor plos genetics gregory p copenhaver editor-in-chief plos genetics www plosgenetics org twitter: @plosgenetics ---------------------------------------------------- comments from the reviewers (if applicable): ---------------------------------------------------- data deposition if you have submitted a research article or front matter that has associated data that are not suitable for deposition in a subject-specific public repository (such as genbank or arrayexpress) one way to make that data available is to deposit it in the dryad digital repository .; journalid=pgenetics&manu=pgenetics-d-23-00875r1 more information about depositing data in dryad is available at http://www datadryad org/depositing . raw data are in s1 data (tab fig 1).; raw data of a b c and d are in s1 data (tab fig 2).; raw data are in s1 data (tab fig 3).; raw data are in s1 data (tab fig 4 ).; raw data are in s1 data (tab fig 5).; raw data of b c and d are in s1 data (tab fig 6).; raw data of b and c are in s1 data (tab fig 7).; all pictures were obtained with axioimager z1 (apotome 213 system zeiss) microscope and images were subsequently processed using fuji and adobe photoshop s1 data (xlsx) click here for additional data file 10 1371/journal pgen 1010897 r001 decision letter 0 copenhaver gregory p editor-in-chief riddiford lynn m academic editor (c) 2023 copenhaver riddiford 2023 copenhaver riddiford https://creativecommons org/licenses/by/4 0/ this is an open access article distributed under the terms of the creative commons attribution license which permits unrestricted use distribution and reproduction in any medium provided the original author and source are credited."

"The authors have declared that no competing interests exist."

"This project is supported by grants PGC2018-098427-B-I00 and PID2021-125661NB-I00 to D.M. and X.F-M. funded by MCIN/AEI/10.13039/501100011033 and by “ERDF A way of making Europe”. The project is supported also by grants 2017 SGR 1030 and 2021 SGR 00417 to D.M. and X.F-M funded by the Departament de Recerca i Universitats de la Generalitat de Catalunya. S.C. was a recipient of a Juan de la Cierva contract FJC2019-041549-I funded by MCIN/AEI /10.13039/501100011033. The funders play no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript."