Targeting autophagy and beyond: Deconvoluting the complexity of Beclin-1 from biological function to cancer therapy.

"Conflicts of interest The authors declare no conflicts of interest."

"This work was supported by the 10.13039/501100001809National Natural Science Foundation of China (Grant Nos. 22177084 and 82173666), Sichuan Science and Technology Program (Grant No. 2022YFQ0054, China), and the Open Research Fund of Chengdu University of Traditional Chinese Medicine State Key Laboratory of Characteristic Chinese Medicine Resources in Southwest China. We also thank some materials in the graphical abstract and figures that are produced by BioRender (https://biorender.com). Bo Liu: Project administration, Supervision, Funding acquisition. Gu He: Conceptualization, Methodology, Supervision. Jing Ye: Data curation, Writing-Original Draft, Visualization. Jin Zhang: Writing-Review & Editing, Visualization. Yanghui Zhu: Data Curation. Lian Wang: Visualization. Xian Jiang: Supervision."