Promoter selectivity of the RhlR quorum-sensing transcription factor receptor in Pseudomonas aeruginosa is coordinated by distinct and overlapping dependencies on C4-homoserine lactone and PqsE.

"plos publication stage vor-update-to-uncorrected-proof publication update 2023-12-20 data availability ebi arrayexpress accession numbers for all rhlr chip-seq data were deposited under e-mtab-12966 ( https://www ebi ac uk/biostudies/arrayexpress/studies/e-mtab-12966 ).; data availability ebi arrayexpress accession numbers for all rhlr chip-seq data were deposited under e-mtab-12966 ( https://www ebi ac uk/biostudies/arrayexpress/studies/e-mtab-12966 ). gaard-andersen section editor plos genetics www plosgenetics org twitter: @plosgenetics ---------------------------------------------------- comments from the reviewers (if applicable): ---------------------------------------------------- data deposition if you have submitted a research article or front matter that has associated data that are not suitable for deposition in a subject-specific public repository (such as genbank or arrayexpress) one way to make that data available is to deposit it in the dryad digital repository .; journalid=pgenetics&manu=pgenetics-d-23-00880r2 more information about depositing data in dryad is available at http://www datadryad org/depositing . the code for data processing and analysis was deposited in the wade lab github at: https://github com/wade-lab . data availability ebi arrayexpress accession numbers for all rhlr chip-seq data were deposited under e-mtab-12966"

"the code for data processing and analysis was deposited in the wade lab github at: https://github com/wade-lab ."

"The authors have declared that no competing interests exist."

"This work was supported by National Institutes of Health grant R01GM14436101, New York Community Trust Foundation grant P19-000454, and Cystic Fibrosis Foundation grant PACZKO21G0 to JEP; NIH Research Supplements to Promote Diversity in Health-Related Research grant 1R01GM14436101-S1 to NJCT and JEP; NIH training grant T32GM132066 to LIP and MWB; and NIH grant R35GM144328 to JTW. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."