SPP1 is associated with adverse prognosis and predicts immunotherapy efficacy in penile cancer.

"the gse57955 microarray dataset (39 pscc samples) from the gene expression omnibus (geo) database was included in our study for further analysis.; availability of data and materials gene expression values based on gene expression omnibus (geo) are accessible through series accession number gse57955. availability of data and materials gene expression values based on gene expression omnibus (geo) are accessible through series accession number gse57955"

"Declarations Ethics approval and consent to participateAll experimental protocols were approved by the Sun Yat-sen University Cancer Center Ethics Committee (No. 2020-FXY-056), and we had acquired informed consent (B2020-073). Consent for publicationThe authors declare that they agree with the publication. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This study was supported by the Fundamental Research Funds for the Central Universities (No. 19ykpy178 to Kai Yao), the Natural Science Foundation of Guangdong Province (No. 2019A1515010197 to Kai Yao) and the Sun Yat-sen University Cancer Center Medical Scientist Training Program (No. 14zxqk08 to Kai Yao)."