Molecular traces of Drosophila hemocytes reveal transcriptomic conservation with vertebrate myeloid cells.

"plos publication stage vor-update-to-uncorrected-proof publication update 2024-01-03 data availability the single-cell dataset generated in this study has been deposited in the ncbi gene expression omnibus (geo) repository under the accession number gse184781 ( https://www ncbi nlm nih gov/geo/query/acc cgi?; data availability the single-cell dataset generated in this study has been deposited in the ncbi gene expression omnibus (geo) repository under the accession number gse184781 ( https://www ncbi nlm nih gov/geo/query/acc cgi? reviewer #1: no reviewer #2: yes: dan hultmark reviewer #3: no ---------------------------------------------------- data deposition if you have submitted a research article or front matter that has associated data that are not suitable for deposition in a subject-specific public repository (such as genbank or arrayexpress) one way to make that data available is to deposit it in the dryad digital repository .; journalid=pgenetics&manu=pgenetics-d-23-00549r1 more information about depositing data in dryad is available at http://www datadryad org/depositing . the cell count of each cell type is indicated in parentheses ( b ) the umi (left) and gene (right) counts in three independent sequencing libraries ( c ) the proportion (left) and count (right) for each cell type from three independent sequencing libraries (different shades of green) ( d ) a conservation map of drosophila hemocytes inferred by integrating gsva and metaneighbor analyses (eps) click here for additional data file s1 table (xlsx) click here for additional data file s2 table (xlsx) click here for additional data file s3 table (xlsx) click here for additional data file s4 table (xlsx) click here for additional data file s5 table (xlsx) click here for additional data file s1 dataset (zip) click here for additional data file. file s1 table (xlsx data availability the single-cell dataset generated in this study has been deposited in the ncbi gene expression omnibus (geo) repository under the accession number gse184781"

"in-house r and python codes used in this study are available on github ( https://github com/sangho1130/dmel_cross_species )."

"The authors have declared that no competing interests exist."

"This work was supported by the National Research Foundation (NRF) of Korea, which is funded by the Ministry of Science & ICT (2020R1A4A1018398, 2021R1A2C3005835, 2022M3E5F1018502, and RS-2023-00207840) to J.-W.N., (2019R1A2C2006848 and RS-2023-00218602) to J.S., and (2020R1A6A3A13076391) to S.-H.Y. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."