Genomic characterization of a unique Panton-Valentine leucocidin-positive community-associated methicillin-resistant <i>Staphylococcus aureus</i> lineage increasingly impacting on Australian indigenous communities.

"in summary wa121 is a distinct and clonally expanding australian pvl-positive ca-mrsa lineage that is increasingly responsible for infections in indigenous communities in northern and western australia wa121 harbours a unique complement of mobile genetic elements and is capable of transferring antimicrobial resistance and virulence determinants to other staphylococci conjugative mobilization dfrg sxt panton-valentine leucocidin pvl-positive st5 ca-mrsa tn4791 tn916 tn7702 tn553 openaccessembargo 0 all illumina sequence reads and genome assemblies completed with long-read data are available in national center for biotechnology information (ncbi) bioproject prjna817299.; all illumina sequence reads and genome assemblies completed with long-read data are available in national center for biotechnology information (ncbi) bioproject prjna817299."

"Conflicts of interest The authors declare that there are no conflicts of interest."

"Funding information J.P.R. is the recipient of an Australian Research Council Future Fellowship (Project ID FT170100235) funded by the Australian Government. This work was partly funded by the Internal Curtin Medical School Research Funding Grant (2021, Curtin University)."