Constitutively active CaMKII Drives B lineage acute lymphoblastic leukemia/lymphoma in tp53 mutant zebrafish.

"head kidney (arrow) is also pictured (tif) click here for additional data file s2 fig histological sections are normal in rag2 : egfp-ca-camkii wild type tp53 mutant and rag2 : egfp-ca-camkii; tp53 mutant fish for (a-c) thymus (d-f) gills (g-i) muscle and (j-l) liver (tif) click here for additional data file s1 data (xlsx) click here for additional data file s1 video (mp4) click here for additional data file s2 video (mp4) click here for additional data file. file s1 data (xlsx"

"The authors have declared that no competing interests exist."

"Support of this research project was derived from the VCU Massey Cancer Center Flow Cytometry Shared Resource and Mouse Model Shared Resource, which were supported with funding from NIH-National Cancer Institute (NCI) Cancer Center Support Grant P30 CA016059. This work was supported by the American Lebanese Syrian Associated Charities (ALSAC) funding (www.stjude.org), National Heart, Lung, and Blood Institute (NHLBI) R00HL097150 (www.nhlbi.nih.gov), and March of Dimes #5-FY14-42 (www.marchofdimes.org) awards to W.K.C. as well as a Massey Cancer Center Pilot Project Grant to R.M.T. and S.C.R. (www.masseycancercenter.org), and VCU Presidential Quest Fund (www.vcu.edu) and National Institute of Child Health and Human Development (NICHD) R03HD103833 to S.C.R. (www.nichd.nih.gov). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."