Loss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.

"the mass spectrometry proteomics datasets have been deposited to the proteomexchange consortium via the pride partner repository [ ] with the dataset identifier pxd045665 reviewer_pxd045665@ebi ac uk . appendix a supplementary data the following are the supplementary data to this article: figures s1-s6 and tables s1-s2 figures s1-s6 and tables s1-s2 table s3 table s3 data availability data will be made available on request. data availability data will be made available on request. acknowledgments this work was supported by the (sfb 10 55776/f73 dk-mcd 10 55776/w1226"

"Declaration of competing interest The authors declare that they have no competing interests."

"This work was supported by the Austrian Science Fund FWF (SFB 10.55776/F73, DK-MCD 10.55776/W1226, 10.55776/P32400, 10.55776/P30882, 10.55776/P28854, 10.55776/I3792, 10.55776/DOC-130, 10.55776/FG12), 10.13039/501100004955Austrian Research Promotion Agency grants 864690 and 870454, Integrative Metabolism Research Center Graz, Austrian Infrastructure Program 2016/2017, the PhD program “Molecular Medicine” and the flagship project “VascHealth” of the Medical University of Graz, BioTechMed-Graz (flagship project DYNIMO), the Province of Styria, and the City of Graz. For open access purposes, the authors have applied a CC BY public copyright license to any author accepted manuscript version arising from this submission. The authors acknowledge the excellent technical assistance of B. Schwarz, A. Ibovnik, S. Rainer, I. Pölzl, and D. Pernitsch (Medical University of Graz, Austria) and thank A. Absenger, M. Singer, and I. Hindler (Medical University of Graz, Austria) for mice maintenance."