ATP7A-dependent copper sequestration contributes to termination of β-CATENIN signaling during early adipogenesis.

"data availability data will be made available on request. acknowledgements this work was supported by the and grant 2 r01 dk071865"

"Declaration of competing interest The authors declare no any financial and personal relationships with other people or organizations that could inappropriately influence this work."

"This work was supported by the 10.13039/100000062NIDDK and OD grant 2 R01 DK071865-14A1. We thank Dr. S. Jayakanthan for providing the adenovirus encoding ATP7B and Dr. W.G. Wong for help and advice with the initial stages of this project. The analysis of proteomes was done at the 10.13039/100007880Johns Hopkins Mass Spectrometry and Proteomics Core supported by the 10.13039/100007880Johns Hopkins 10.13039/100005902Institute for Clinical and Translational Research/Translational Science Cores (NCATS center grant UL1 TR003098); the 10.13039/100007880JHU 10.13039/100011566Sidney Kimmel Comprehensive Cancer Center (NCI center grant P30 CA006973) and the Hopkins Digestive Diseases Basic and Translational Research Core Center (NIDDK center grant P30 DK089502). Grants from Dora Plus 1.2 and Kristjan Jaak Scholarship Programmes were awarded by Archimedes Foundation (Education and Youth Board, Estonia) to E.K. H. Yang: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing. E. Kabin: Data curation, Formal analysis, Investigation, Writing – review & editing. Y. Dong: Data curation, Formal analysis, Investigation, Writing – review & editing. X. Zhang: Formal analysis, Investigation. M. Ralle: Formal analysis, Investigation, Methodology. S. Lutsenko: Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – review & editing."