Identification of AgRP cells in the murine hindbrain that drive feeding.

"to gain insight into agrp cells in the ap of adult mice we analyzed the publicly available single-nuclei rnaseq (snrnaseq) dataset which contains pooled micro-dissected ap tissues from adult mice (geo accession number gse160938 ) [ ].; appendix a supplementary data the following are the supplementary data to this article: multimedia component 1 multimedia component 1 multimedia component 2 multimedia component 2 data availability single cell rnaseq data from this study are deposited in the ncbi geo database (geo accession number gse204865). data availability single cell rnaseq data from this study are deposited in the ncbi geo database (geo accession number gse204865"

"Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"This study was supported by the Joseph and Vera Long Foundation and the Sandler Program for Breakthrough Biomedical Research (PBBR) to A.W.X. The work was also supported in part by the Lilly Research Award Program (LRAP) fund to A.W.X. and P.J.E., the Lilly Innovation Fellowship Award (LIFA) to T.P.B and E.Y., 10.13039/501100003725National Research Foundation of Korea – NRF 2021R1A6A3A14044733 to E.H., and NIH grants R01 DK119169 and P01 DK119130-03 to K.W.W. The work was partly supported by the Mouse Metabolism Core at the UCSF Nutrition Obesity Center (NIH NIDDK P30DK098722), the Microscopy Core at the UCSF Diabetes Endocrinology Research Center (NIH NIDDK P30 DK63720), and the Gladstone Bioinformatics Core. Author Contributions: T. P. B., E. Y. and A.W.X. designed the experiments and analyzed the data. T.P.B., E.H., E.Y., K.A., E.V., M.V., F.M. carried out experiments and analyzed the data. P.J.E., C.V. and K.W.W. provided critical input to the study and the manuscript. T. P. B. E.H., K.W.W. and A.W.X. wrote the manuscript. Graphics were created with BioRender. Tomas P. Bachor: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing, Funding acquisition. Eunsang Hwang: Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing. Ernie Yulyaningsih: Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology. Kush Attal: Data curation, Formal analysis. Francois Mifsud: Data curation, Formal analysis. Viana Pham: Data curation, Formal analysis. Eirini Vagena: Data curation, Formal analysis. Renzo Huarcaya: Data curation, Formal analysis. Martin Valdearcos: Data curation, Formal analysis. Christian Vaisse: Data curation, Formal analysis, Writing – review & editing. Kevin W. Williams: Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing. Paul J. Emmerson: Funding acquisition, Supervision, Writing – review & editing. Allison W. Xu: Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing."