Heterologous Sarbecovirus Receptor Binding Domains as Scaffolds for SARS-CoV-2 Receptor Binding Motif Presentation.

"The authors declare no competing financial interest."

"The authors thank Dr. Jason McLellan from University of Texas, Austin for the spike plasmid. They also thank Nir Hacohen and Michael Farzan for the kind gift of the ACE2 expressing 293T cells and the Center for Macromolecular Interactions at Harvard Medical School for experimental support specifically, Kelly Arnett . The authors acknowledge funding from NIH R01s AI146779 (A.G.S); AI174875 (A.B.B.); AI155447, AI137057, and AI153098 (D.L.); a Massachusetts Consortium on Pathogenesis Readiness (MassCPR) grant (A.G.S. and A.B.B.); NIH P01 AI168347 (A.G.S.); training grants: NIGMS T32 GM007753 (B.M.H.), F31 Al138368 (M.S.), F30 AI160908 (B.M.H.). ABB. National Institutes for Drug Abuse (NIDA) Avenir New Innovator Award DP2DA040254 (A.B.B.) and CDC subcontract 200-2016-91773-T.O.2 (A.B.B.) Author Contributions: Conceptualization, B.M.H., A.G.S.; Methodology, B.M.H., M.S., E.C.L., A.G.S.; Investigation, B.M.H., M.S., E.C.L., K.J.S.D., M.L.S., M.L.V., A.H.C.; Writing—original draft, B.M.H. and A.G.S.; Writing—review and editing, all authors; Funding acquisition, A.B.B., D.L., A.G.S.; Supervision, A.B.B., D.L., A.G.S."