Targeting cAMP in D1-MSNs in the nucleus accumbens, a new rapid antidepressant strategy.

"Conflicts of interest The authors declare no conflict of interest."

"This study was supported by 10.13039/501100001809National Natural Science Foundation of China (No. 82104278), Leading Technology Foundation Research Project of Jiangsu Province (No. BK20192005, China), National Key Project of Science and Technology for Innovation Drugs of China (No. 2017ZX09301013), CAMS Innovation Fund for Medical Sciences (CIFMS, No. 2021-I2M-5-011, China), Sanming Project of Medicine in Shenzhen (No. SZSM201801060, China), Project of State Key Laboratory of Natural Medicines, China Pharmaceutical University (No. SKLNMKF202203, China), National Innovation and Entrepreneurship Training Program for Undergraduate, China Pharmaceutical University (Nos. 2023103161381 and 2023103161287, China). The authors would like to thank the sharing platform for the use of large-scale experimental apparatuses at the State Key Laboratory of National Medicines, China Pharmaceutical University."