Acetyl-CoA synthetase (ACSS2) does not generate butyryl- and crotonyl-CoA.

"data availability data will be made available on request. appendix a supplementary data to this article can be found online at https://doi"

"Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"Funding This work was supported by the Univ. Grenoble Alpes CDP SYMER program (ANR-15-IDEX-02; US, SK, CP), the Institut Universitaire de France (IUF) and the French National Research Agency projects NME_CoA (ANR-23-CE14-0050; US, SK), Episperm4 (ANR-19-CE12-0014; SK, CP) and EpiSperm5 (ANR-23-CE12-0028; SK, CP). Molecular modeling was supported by the Grenoble Partnership for Structural Biology (PSB) via FRISBI (ANR-10-INBS-05-02) and GRAL (financed by CBH-EUR-GS, ANR-17-EURE-0003). The Grenoble GEMELI metabolomics facility was supported by the Region Auvergne-Rhone-Alpes."