Adrenarche-accompanied rise of adrenal sex steroid precursors prevents NAFLD in Young Female rats by converting into active androgens and inactivating hepatic Srebf1 signaling.

Publication Year: 2024

DOI:
10.1186/s12864-024-10107-6

PMCID:
PMC10875776

PMID:
38369486

Journal Information

Full Title: BMC Genomics

Abbreviation: BMC Genomics

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Declarations Ethics approval and consent to participateAll methods were carried out in accordance with relevant guidelines and regulations. The protocols for all animal experiments were approved by the Animal Welfare Committee of Sichuan Agricultural University, and all methods strictly obeyed the Guide for the ARRIVE (Animal Research: Reporting of in Vivo Experiments) guidelines 2.0 [42]. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

Evidence found in paper:

"Funding This work was funded by National Natural Science Foundation of China (Grant No. 32272826) and the Natural Science Foundation of Sichuan Province (Grant No. 2023NSFSC0240)."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025