Transcriptomics and metabolomics analysis reveal the dietary copper deficiency and supplementation effects of liver gene expression and metabolite change in grazing sheep.

"availability of data and materials the sequencing data will be deposited in the public archive of ncbi under the bioproject id prjna1024932. table s5 . the raw data availability of data and materials the sequencing data will be deposited in the public archive of ncbi under the bioproject id prjna1024932"

"Declarations Ethics approval and consent to participateThe experimental protocol was approved by the Inner Mongolia University Animal Care and Use Committee (IMU-2020-sheep-040). All methods are reported in accordance with ARRIVE guidelines for the reporting of animal experiments. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This research was funded by the Research Support Program for the Introduction of High-level Talents at the Provincial Level in Inner Mongolia Autonomous Region (12000–15042245) and the Research Foundation for Advanced Talents of Inner Mongolia University."