Extreme restructuring of cis-regulatory regions controlling a deeply conserved plant stem cell regulator.

"raw locule counts are available in s1 data .; all crispr-cas9 alleles generated in this study are described in s2 data and sequencing traces are provided in s3 data .; a comparison of these analyses are displayed in s4 data s1 fig heatmap representations of the atclv3 alleles used in interaction tests with their locule number quantifications.; purple arrowheads grnas (tif) s1 table (pdf) s2 table grnas used in arabidopsis crispr grnas used in tomato crispr and genotyping/sequencing primers (pdf) s1 data (xlsx) s2 data (xlsx) s3 data (zip) s4 data (xlsx) we thank members of the lippman laboratory for comments discussions and assistance with phenotyping; j van eck and q jiang for performing tomato transformations; and t mulligan k schlecht a krainer b fitzgerald and s qiao for assistance with plant care."

"I have read the journal’s policy and the authors of this manuscript have the following competing interests: Z.B.L. is a consultant for and a member of the Scientific Strategy Board of Inari Agriculture."

"This research was supported by the Cold Spring Harbor Laboratory School of Biological Sciences, and the Natural Sciences and Engineering Research Council of Canada Postgraduate Scholarships – Doctoral program to D.C., the National Institute Of General Medical Sciences of the National Institutes of Health under Award Number K99GM149939 (the content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health) to S.Z., and the Howard Hughes Medical Institute and National Science Foundation Plant Genome Research Program grant IOS-2129189 to Z.B.L. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."